An INTERVIEW with Mark Schena, Ph.D.
ESI Special Topics,
February 2003
Citing URL - http://www.esi-topics.com/arab/interviews/MarkSchena.html
 hen Special Topics analyzed the top papers in
Arabidopsis
research over the past decade, the number one paper was
"Quantitative monitoring of gene expression patterns with a
complementary DNA microarray," (Science 270[5235]: 467-70,
20 October 1995), with 1,287 citations to date. In the brief interview
below, lead author Dr. Mark Schena discusses this paper. Dr. Schena is
a Visiting Scholar at TeleChem International, Inc. in California. Dr.
Schena’s work can be found in the fields of Biology &
Biochemistry, Clinical Medicine, and Plant & Animal Science in the
ISI
Essential
Science Indicators
Web product.
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 Why do you think your paper is highly cited?
The ‘95 Science paper represents the first publication on
microarrays, and the technology has become very widely used and cited
for this reason.
Can you describe the significance of your work for the field of
Arabidopsis research?
Microarray analysis enables researchers to explore fundamental
questions at the level of the entire Arabidopsis genome.
Whole-genome analysis provides unprecedented insights into plant
development, light signaling, hormone action, and the like, which are
impossible to obtain with any other technology.
What were the circumstances that led you to do this research?
Ron Davis and I were trying to devise a way to study the function
of a homeobox gene family that we isolated in the early 1990s, and
developed the DNA microarray for this purpose. I knew the work was
important, but had no idea the technology would proliferate as quickly
as it has.
Mark Schena, Ph.D.
TeleChem International, Inc.
Sunnyvale, CA, USA
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ESI Special Topics,
February 2003
Citing URL - http://www.esi-topics.com/arab/interviews/MarkSchena.html
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