Full Record & Graph Of A Top 20 Paper in Uterine Fibroids

#3 Paper of the Top 20 Papers in Uterine Fibroids

Title:

THE MAINE-WOMENS-HEALTH-STUDY .1. OUTCOMES OF HYSTERECTOMY

Authors:

CARLSON KJ, MILLER BA, FOWLER FJ

Source:

OBSTETRICS AND GYNECOLOGY 83 (4): 556-565 APR 1994

Document Type:

Article

Language:

English

Cited References:

Times Cited:

173

Abstract:

Objective: To assess the effect of hysterectomy for nonmalignant conditions on symptoms and quality of life and to identify adverse effects 1 year after surgery.
Methods: The Maine Women's Health Study was a prospective cohort study of 418 women ages 25-50 years undergoing hysterectomy for any nonmalignant condition. Patients recruited from the practices of 63 physicians performing hysterectomy throughout Maine were interviewed at the time of surgery and 3, 6, and 12 months later. Clinical and hospitalization data were obtained from physician reports and from a statewide hospital discharge data base. The primary outcomes of interest were symptom relief, changes in quality of life, and the development of new symptoms or problems during the year following surgery.

Results: The most frequent indications for hysterectomy were leiomyomas (35%), abnormal bleeding (22%), and chronic pelvic pain (18%). For these indications, hysterectomy resulted in marked improvements in a range of symptoms, including pelvic pain, urinary symptoms, fatigue, psychological symptoms, and sexual dysfunction. Significant improvements in scores for indices of mental health, general health, and activity were evident at 6 months and sustained at 1 year. New problems after hysterectomy (measured in those free of the symptom preoperatively) included hot flashes (13%), weight gain (12%), depression (8%), and lack of interest in sex (7%).

Conclusions: Hysterectomy is highly effective for relief of symptoms associated with common nonmalignant gynecologic conditions. Symptom relief following hysterectomy is associated with a marked improvement in quality of life. New problems are reported after hysterectomy by a limited number of women.

Keywords Plus:

TOTAL ABDOMINAL HYSTERECTOMY; VAGINAL HYSTERECTOMY; UNITED-STATES

Addresses:

CARLSON KJ (reprint author), MASSACHUSETTS GEN HOSP, CTR MED PRACTICES EVALUAT, 50 STANIFORD ST, 9TH FLOOR, BOSTON, MA 02114 USA
MAINE MED ASSESSMENT FDN, PORTLAND, ME USA
HARVARD UNIV, SCH MED, BOSTON, MA 02115 USA
UNIV MASSACHUSETTS, CTR SURVEY RES, BOSTON, MA 02125 USA

Publisher:

ELSEVIER SCIENCE INC, 655 AVENUE OF THE AMERICAS, NEW YORK, NY 10010

Subject Category:

OBSTETRICS & GYNECOLOGY

IDS Number:

ND231

ISSN:

0029-7844

Graph - Number of Citations (by year):

Graph not available for this paper.

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ESI Special Topics, March 2005
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