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Pharmacology & Toxicology

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ESI Special Topics, January 2008
Citing URL: http://www.esi-topics.com/fmf/maps/january2008-map.html

This Research Front on ORGANOCATALYTIC DOMINO REACTIONS from the field of Pharmacology & Toxicology was selected for mapping from the list of Fast Moving Fronts for January 2008. The map is a diagrammatic representation of the 29 core papers comprising the front. Each circle represents a highly cited paper whose bibliographic information is displayed when the user clicks on the circle. The lines between circles represent the strongest co-citation links for each paper (that is, indicating that the papers are frequently cited together). Papers close to each other on the map are generally more highly co-cited. The most recent paper(s) are indicated in red.


Fast Moving Fronts Comments
David MacMillan talks about his highly cited paper, "Enantioselective organo-cascade catalysis," (J AM CHEM SOC, 26 127 (43): 15051-15053, NOV 2 2005) which is this month's emerging research front in Pharmacology & Toxicology. This paper is represented in the map below.

Yang-2005 Huang-2005 Marigo-2005 Marigo-2006 Marigo-2006 Enders-2006 Brandau-2006 Chen-2006 Wang-2006 Lelais-2006 Govender-2006 Wang-2006 Brandau-2006 Rios-2006 Palomo-2006 Enders-2007 Wang-2007 Vesely-2007 Li-2007 Gaunt-2007 Zu-2007 Song-2007 Carlone-2007 Liu-2007 Bertelsen-2007 Diner-2007 Enders-2007 Li-2007 Pellissier-2007
 ORGANOCATALYTIC DOMINO REACTIONS  


 Core Papers 


Label: Huang-2005
Title: Enantioselective organo-cascade catalysis
Journal: J AM CHEM SOC, 127 (43): 15051-15053 NOV 2 2005
Citations: 81
Authors: Huang, Y;Waiji, AM;Larsen, CH;MacMillan, DWC
Addresses:
CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA
CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA
Fast Moving Fronts Comments
by 
David MacMillan - (from March 2007)


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Label: Marigo-2005
Title: Asymmetric multicomponent domino reactions and highly enantioselective conjugated addition of thiols to alpha,beta-unsaturated aldehydes
Journal: J AM CHEM SOC, 127 (45): 15710-15711 NOV 16 2005
Citations: 68
Authors: Marigo, M;Schulte, T;Franzen, J;Jorgensen, KA
Addresses:
Aarhus Univ, Danish Natl Res Fdn, Ctr Catalysis, Dept Chem, DK-8000 Aarhus, Denmark
Aarhus Univ, Danish Natl Res Fdn, Ctr Catalysis, Dept Chem, DK-8000 Aarhus, Denmark


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Label: Enders-2006
Title: Control of four stereocentres in a triple cascade organocatalytic reaction
Journal: NATURE, 441 (7095): 861-863 JUN 15 2006
Citations: 59
Authors: Enders, D;Huttl, MRM;Grondal, C;Raabe, G
Addresses:
RWTH Aachen Univ, Inst Organ Chem, Landoltweg 1, D-52074 Aachen, Germany
RWTH Aachen Univ, Inst Organ Chem, D-52074 Aachen, Germany


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Label: Yang-2005
Title: Catalytic asymmetric reductive Michael cyclization
Journal: J AM CHEM SOC, 127 (43): 15036-15037 NOV 2 2005
Citations: 53
Authors: Yang, JW;Fonseca, MTH;List, B
Addresses:
Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany
Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany


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Label: Wang-2006
Title: Enantioselective organocatalytic tandem Michael-aldol reactions: One-pot synthesis of chiral thiochromenes
Journal: J AM CHEM SOC, 128 (32): 10354-10355 AUG 16 2006
Citations: 36
Authors: Wang, W;Li, H;Wang, J;Zu, LS
Addresses:
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA


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Label: Lelais-2006
Title: Modern strategies in organic catalysis: The advent and development of iminium activation
Journal: ALDRICHIM ACTA, 39 (3): 79-87 2006
Citations: 34
Authors: Lelais, G;MacMillan, DWC
Addresses:
CALTECH, Dept Chem, 1200 E Calif Blvd,Mail Code 164-30, Pasadena, CA 91125 USA
CALTECH, Dept Chem, Pasadena, CA 91125 USA


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Label: Marigo-2006
Title: Organocatalytic direct asymmetric alpha-heteroatom functionalization of aldehydes and ketones
Journal: CHEM COMMUN, (19): 2001-2011 2006
Citations: 27
Authors: Marigo, M;Jorgensen, KA
Addresses:
Aarhus Univ, Dept Chem, Ctr Catalysis, Danish Natl Res Fdn, DK-8000 Aarhus C, Denmark
Aarhus Univ, Dept Chem, Ctr Catalysis, Danish Natl Res Fdn, DK-8000 Aarhus C, Denmark


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Label: Brandau-2006
Title: Organocatalytic conjugate addition of malonates to alpha,beta-unsaturated aldehydes: Asymmetric formal synthesis of (-)-paroxetine, chiral lactams, and lactones
Journal: ANGEW CHEM INT ED, 45 (26): 4305-4309 2006
Citations: 26
Authors: Brandau, S;Landa, A;Franzen, J;Marigo, M;Jorgensen, KA
Addresses:
Aarhus Univ, Danish Natl Res Fdn, Ctr Catalysis, Dept Chem, DK-8000 Aarhus C, Denmark
Aarhus Univ, Danish Natl Res Fdn, Ctr Catalysis, Dept Chem, DK-8000 Aarhus C, Denmark


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Label: Chen-2006
Title: Enantioselective organocatalytic amine conjugate addition
Journal: J AM CHEM SOC, 128 (29): 9328-9329 JUL 26 2006
Citations: 19
Authors: Chen, YK;Yoshida, M;MacMillan, DWC
Addresses:
CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA
CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA


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Label: Marigo-2006
Title: One-pot organocatalytic domino Michael-aldol and intramolecular S(N)2 reactions. Asymmetric synthesis of highly functionalized epoxycyclohexanone derivatives
Journal: J AM CHEM SOC, 128 (16): 5475-5479 APR 26 2006
Citations: 17
Authors: Marigo, M;Bertelsen, S;Landa, A;Jorgensen, KA
Addresses:
Aarhus Univ, Ctr Catalysis, Dept Chem, Danish Natl Res Fdn, DK-8000 Aarhus C, Denmark
Aarhus Univ, Ctr Catalysis, Dept Chem, Danish Natl Res Fdn, DK-8000 Aarhus C, Denmark


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Label: Palomo-2006
Title: Diarylprolinol ethers: Expanding the potential of enamine/iminium-ion catalysis
Journal: ANGEW CHEM INT ED, 45 (47): 7876-7880 2006
Citations: 17
Authors: Palomo, C;Mielgo, A
Addresses:
Univ Pais Vasco, Fac Quim, Dept Quim Organ 1, Apdo 1072, San Sebastian 20080, Spain
Univ Pais Vasco, Fac Quim, Dept Quim Organ 1, San Sebastian 20080, Spain


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Label: Govender-2006
Title: Organocatalytic synthesis of chral benzopyrans
Journal: TETRAHEDRON-ASYMMETRY, 17 (12): 1763-1767 JUL 31 2006
Citations: 16
Authors: Govender, T;Hojabri, L;Moghaddam, FM;Arvidsson, PI
Addresses:
Dept Biochem & Organ Chem, Box 573, SE-75123 Uppsala, Sweden
Dept Biochem & Organ Chem, SE-75123 Uppsala, Sweden
Sharif Univ Technol, Dept Chem, Tehran, Iran


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Label: Brandau-2006
Title: Asymmetric synthesis of highly functionalized tetrahydrothiophenes by organocatalytic domino reactions
Journal: J AM CHEM SOC, 128 (46): 14986-14991 NOV 22 2006
Citations: 15
Authors: Brandau, S;Maerten, E;Jorgensen, KA
Addresses:
Aarhus Univ, Dept Chem, Danish Natl Res Fdn, Ctr Catalysis, DK-8000 Aarhus C, Denmark
Aarhus Univ, Dept Chem, Danish Natl Res Fdn, Ctr Catalysis, DK-8000 Aarhus C, Denmark


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Label: Rios-2006
Title: Highly enantioselective synthesis of 2H-1-benzothiopyrans by a catalytic domino reaction
Journal: TETRAHEDRON LETT, 47 (48): 8547-8551 NOV 27 2006
Citations: 15
Authors: Rios, R;Sunden, H;Ibrahem, I;Zhao, GL;Eriksson, L;Cordova, A
Addresses:
Stockholm Univ, Arrhenius Lab, Dept Organ Chem, SE-10691 Stockholm, Sweden
Stockholm Univ, Arrhenius Lab, Dept Organ Chem, SE-10691 Stockholm, Sweden


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Label: Wang-2006
Title: Organocatalytic enantioselective conjugate additions to enones
Journal: J AM CHEM SOC, 128 (39): 12652-12653 OCT 4 2006
Citations: 14
Authors: Wang, J;Li, H;Zu, LS;Jiang, W;Xie, HX;Duan, WH;Wang, W
Addresses:
E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA


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Label: Enders-2007
Title: Asymmetric organocatalytic domino reactions
Journal: ANGEW CHEM INT ED, 46 (10): 1570-1581 2007
Citations: 13
Authors: Enders, D;Grondal, C;Huttl, MRM
Addresses:
Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52074 Aachen, Germany
Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany


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Label: Enders-2007
Title: Organocatalytic one-pot asymmetric synthesis of functionalized tricyclic carbon frameworks from a triple-cascade/Diels-Alder sequence
Journal: ANGEW CHEM INT ED, 46 (3): 467-469 2007
Citations: 9
Authors: Enders, D;Huttl, MRM;Runsink, J;Raabe, G;Wendt, B
Addresses:
Rhein Westfal TH Aachen, Inst Organ Chem, Landoltweg 1, D-52074 Aachen, Germany
Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany


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Label: Li-2007
Title: One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction
Journal: CHEM COMMUN, (5): 507-509 2007
Citations: 9
Authors: Li, H;Wang, J;E-Nunu, T;Zu, LS;Jiang, W;Wei, S;Wang, W
Addresses:
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA
Nanjing Normal Univ, Dept Chem, Nanjing 210097, Peoples R China


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Label: Carlone-2007
Title: A new approach for an organocatalytic multicomponent domino asymmetric reaction
Journal: ANGEW CHEM INT ED, 46 (7): 1101-1104 2007
Citations: 8
Authors: Carlone, A;Cabrera, S;Marigo, M;Jorgensen, KA
Addresses:
Aarhus Univ, Ctr Catalysis, Danish Natl Res Fdn, Dept Chem, DK-8000 Aarhus C, Denmark
Aarhus Univ, Ctr Catalysis, Danish Natl Res Fdn, Dept Chem, DK-8000 Aarhus C, Denmark


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Label: Vesely-2007
Title: Organocatalytic enantioselective aziridination of alpha,beta-unsaturated aldehydes
Journal: ANGEW CHEM INT ED, 46 (5): 778-781 2007
Citations: 7
Authors: Vesely, J;Ibrahem, I;Zhao, GL;Rios, R;Cordova, A
Addresses:
Univ Stockholm, Arrhenius Lab, Dept Organ Chem, S-10691 Stockholm, Sweden
Univ Stockholm, Arrhenius Lab, Dept Organ Chem, S-10691 Stockholm, Sweden


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Label: Wang-2007
Title: Control of diastereoselectivity in tandem asymmetric reactions generating nonadjacent stereocenters with bifunctional catalysis by cinchona alkaloids
Journal: J AM CHEM SOC, 129 (4): 768-769 JAN 31 2007
Citations: 7
Authors: Wang, BM;Wu, FH;Wang, Y;Liu, XF;Deng, L
Addresses:
Brandeis Univ, Dept Chem, Waltham, MA 02454 USA
Brandeis Univ, Dept Chem, Waltham, MA 02454 USA


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Label: Gaunt-2007
Title: Enantioselective organocatalysis
Journal: DRUG DISCOV TODAY, 12 (1-2): 8-27 JAN 2007
Citations: 6
Authors: Gaunt, MJ;Johansson, CCC;McNally, A;Vo, NT
Addresses:
Univ Cambridge, Dept Chem, Lensfield Rd, Cambridge CB2 1EW, England
Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England


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Label: Li-2007
Title: Chiral diphenylprolinol TES ether promoted conjugate addition-aldol-dehydration reactions between alpha,beta-unsaturated aldehydes and 2-N-protected amino benzaldehydes
Journal: ORG LETT, 9 (6): 965-968 MAR 15 2007
Citations: 6
Authors: Li, H;Wang, J;Xie, HX;Zu, LS;Jiang, W;Duesler, EN;Wang, W
Addresses:
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA


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Label: Diner-2007
Title: Enantioselective organocatalytic conjugate addition of N heterocycles to alpha,beta-unsaturated aldehydes
Journal: ANGEW CHEM INT ED, 46 (12): 1983-1987 2007
Citations: 5
Authors: Diner, P;Nielsen, M;Marigo, M;Jorgensen, KA
Addresses:
Aarhus Univ, Dept Chem, Ctr Catalysis, Danish Natl Res Fdn, DK-8000 Aarhus C, Denmark
Aarhus Univ, Dept Chem, Ctr Catalysis, Danish Natl Res Fdn, DK-8000 Aarhus C, Denmark


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Label: Bertelsen-2007
Title: Asymmetric organocatalytic beta-hydroxylation of alpha,beta-unsaturated aldehydes
Journal: J AM CHEM SOC, 129 (6): 1536-+ FEB 14 2007
Citations: 3
Authors: Bertelsen, S;Diner, P;Johansen, RL;Jorgensen, KA
Addresses:
Univ Aarhus, Dept Chem, Ctr Catalysis, Danish Natl Res Fdn, DK-8000 Aarhus C, Denmark
Univ Aarhus, Dept Chem, Ctr Catalysis, Danish Natl Res Fdn, DK-8000 Aarhus C, Denmark


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Label: Liu-2007
Title: Organocatalytic and highly stereoselective direct vinylogous mannich reaction
Journal: J AM CHEM SOC, 129 (7): 1878-+ FEB 21 2007
Citations: 3
Authors: Liu, TY;Cui, HL;Long, J;Li, BJ;Wu, Y;Ding, LS;Chen, YC
Addresses:
Sichuan Univ, W China Sch Pharm, Key Lab Drug Targeting Educ Minist, Chengdu 610041, Peoples R China
Sichuan Univ, W China Sch Pharm, Key Lab Drug Targeting Educ Minist, Chengdu 610041, Peoples R China
Sichuan Univ, Dept Med Chem, W China Sch Pharm, Chengdu 610041, Peoples R China
Sichuan Univ, W China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China
Chinese Acad Sci, Chengdu Inst Biol, Chengdu, Peoples R China


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Label: Pellissier-2007
Title: Asymmetric 1,3-dipolar cycloadditions
Journal: TETRAHEDRON, 63 (16): 3235-3285 APR 16 2007
Citations: 3
Authors: Pellissier, H
Addresses:
Univ Paul Cezanne Aix Marseille III, UMR n 6180, Ave Esc,Normandie Niemen, F-13397 Marseille, France
Univ Paul Cezanne Aix Marseille III, UMR n 6180, F-13397 Marseille, France


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Label: Song-2007
Title: Asymmetric Mannich reactions with in situ generation of carbamate-protected imines by an organic catalyst
Journal: ORG LETT, 9 (4): 603-606 FEB 15 2007
Citations: 3
Authors: Song, J;Shih, HW;Deng, L
Addresses:
Brandeis Univ, Dept Chem, Waltham, MA 02454 USA
Brandeis Univ, Dept Chem, Waltham, MA 02454 USA


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Label: Zu-2007
Title: Cascade Michael-Aldol reactions promoted by hydrogen bonding mediated catalysis
Journal: J AM CHEM SOC, 129 (5): 1036-1037 FEB 7 2007
Citations: 3
Authors: Zu, LS;Wang, J;Li, H;Xie, HX;Jiang, W;Wang, W
Addresses:
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA
Univ New Mexico, Dept Chem, Albuquerque, NM 87131 USA


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ESI Special Topics, January 2008
Citing URL: http://www.esi-topics.com/fmf/maps/january2008-map.html

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