***Article 1
Total Cites: 2567
Article Title: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
Authors: Elbashir, SM, Harborth, J, Lendeckel, W, Yalcin, A, Weber, K, Tuschl, T
Journal: NATURE
Volume: 411
Page: 494-498
Year: 2001
Addresses: 
· Max Planck Inst Biophys Chem, Dept Cellular Biochem, Gottingen, Germany
· Max Planck Inst Biophys Chem, Dept Biochem & Cell Biol, Gottingen, Germany

***Article 2
Total Cites: 2459
Article Title: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Authors: Fire, A, Xu, SQ, Montgomery, MK, Kostas, SA, Driver, SE, Mello, CC
Journal: NATURE
Volume: 391
Page: 806-811
Year: 1998
Addresses: 
· Carnegie Inst Washington, Dept Embryol, Baltimore, MD, USA
· Johns Hopkins Univ, Biol Grad Program, Baltimore, MD, USA
· Univ Massachusetts, Ctr Canc, Dept Cell Biol, Program Mol Med, Worcester, MA, USA

***Article 3
Total Cites: 1824
Article Title: Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
Authors: Herman, JG, Graff, JR, Myohanen, S, Nelkin, BD, Baylin, SB
Journal: P NATL ACAD SCI USA
Volume: 93
Page: 9821-9826
Year: 1996
Addresses: 
· JOHNS HOPKINS MED INST, DEPT MED, BALTIMORE, MD, USA

***Article 4
Total Cites: 1046
Article Title: RNA interference
Authors: Hannon, GJ
Journal: NATURE
Volume: 418
Page: 244-251
Year: 2002
Addresses: 
· Cold Spring Harbor Lab, Cold Spring Harbor, NY, USA

***Article 5
Total Cites: 904
Article Title: Role for a bidentate ribonuclease in the initiation step of RNA interference
Authors: Bernstein, E, Caudy, AA, Hammond, SM, Hannon, GJ
Journal: NATURE
Volume: 409
Page: 363-366
Year: 2001
Addresses: 
· Cold Spring Harbor Lab, Cold Spring Harbor, NY, USA
· Watson Sch Biol Sci, Cold Spring Harbor, NY, USA
· SUNY Stony Brook, Grad Program Genet, Stony Brook, NY, USA
· Genetica, Cambridge, MA, USA

***Article 6
Total Cites: 899
Article Title: Cancer epigenetics comes of age
Authors: Jones, PA, Laird, PW
Journal: NATURE GENETICS
Volume: 21
Page: 163-167
Year: 1999
Addresses: 
· Univ So Calif, Sch Med, Kenneth Norris Jr Comprehens Canc Ctr, Dept Biochem & Mol Biol, Los Angeles, CA, USA
· Univ So Calif, Sch Med, Kenneth Norris Jr Comprehens Canc Ctr, Dept Surg, Los Angeles, CA, USA

***Article 7
Total Cites: 881
Article Title: RNA interference is mediated by 21-and 22-nucleotide RNAs
Authors: Elbashir, SM, Lendeckel, W, Tuschl, T
Journal: GENE DEV
Volume: 15
Page: 188-200
Year: 2001
Addresses: 
· Max Planck Inst Biophys Chem, Dept Cellular Biochem, Gottingen, Germany

***Article 8
Total Cites: 851
Article Title: Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
Authors: Jones, PL, Veenstra, GJC, Wade, PA, Vermaak, D, Kass, SU, Landsberger, N, Strouboulis, J, Wolffe, AP
Journal: NATURE GENETICS
Volume: 19
Page: 187-191
Year: 1998
Addresses: 
· NICHHD, Mol Embryol Lab, NIH, Bethesda, MD, USA
· Janssen Res Fdn, Dept Expt Mol Biol, Beerse, Belgium
· Univ Varese, Dipartimento Biol Strutturale & Funz, Varese, Italy

***Article 9
Total Cites: 783
Article Title: An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
Authors: Hammond, SM, Bernstein, E, Beach, D, Hannon, GJ
Journal: NATURE
Volume: 404
Page: 293-296
Year: 2000
Addresses: 
· Cold Spring Harbor Lab, Cold Spring Harbor, NY, USA
· Genet Inc, Cold Spring Harbor, NY, USA
· SUNY Stony Brook, Grad Program Genet, Stony Brook, NY, USA
· Univ Coll London, Wolfson Inst Biol Sci, London, England

***Article 10
Total Cites: 768
Article Title: RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
Authors: Zamore, PD, Tuschl, T, Sharp, PA, Bartel, DP
Journal: CELL
Volume: 101
Page: 25-33
Year: 2000
Addresses: 
· Univ Massachusetts, Sch Med, Dept Biochem & Mol Biol, Worcester, MA, USA
· Max Planck Inst Biophys Chem, Dept Cellular Biochem, Gottingen, Germany
· MIT, Ctr Canc Res, Cambridge, MA, USA
· MIT, Dept Biol, Cambridge, MA, USA
· Whitehead Inst Biomed Res, Cambridge, MA, USA

***Article 11
Total Cites: 764
Article Title: The fundamental role of epigenetic events in cancer
Authors: Jones, PA, Baylin, SB
Journal: NATURE REVIEWS GENETICS
Volume: 3
Page: 415-428
Year: 2002
Addresses: 
· USC, Keck Sch Med, Kenneth Norris Jr Comprehens Canc Ctr, Dept Urol, Los Angeles, CA, USA
· USC, Keck Sch Med, Kenneth Norris Jr Comprehens Canc Ctr, Dept Biochem, Los Angeles, CA, USA
· USC, Keck Sch Med, Kenneth Norris Jr Comprehens Canc Ctr, Dept Mol Biol, Los Angeles, CA, USA
· Johns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Dept Oncol, Baltimore, MD, USA
· Johns Hopkins Med Inst, Sidney Kimmel Comprehens Canc Ctr, Dept Med, Baltimore, MD, USA

***Article 12
Total Cites: 747
Article Title: A species of small antisense RNA in posttranscriptional gene silencing in plants
Authors: Hamilton, AJ, Baulcombe, DC
Journal: SCIENCE
Volume: 286
Page: 950-952
Year: 1999
Addresses: 
· John Innes Ctr Plant Sci Res, Sainsbury Lab, Norwich, England

***Article 13
Total Cites: 690
Article Title: Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
Authors: Bannister, AJ, Zegerman, P, Partridge, JF, Miska, EA, Thomas, JO, Allshire, RC, Kouzarides, T
Journal: NATURE
Volume: 410
Page: 120-124
Year: 2001
Addresses: 
· Univ Cambridge, Wellcome CRC Inst, Cambridge, England
· Univ Cambridge, Dept Pathol, Cambridge, England
· Western Gen Hosp, MRC, Human Genet Unit, Edinburgh, Scotland
· Univ Cambridge, Dept Biochem, Cambridge, England

***Article 14
Total Cites: 677
Article Title: Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
Authors: Lachner, M, Ocarroll, N, Rea, S, Mechtler, K, Jenuwein, T
Journal: NATURE
Volume: 410
Page: 116-120
Year: 2001
Addresses: 
· Vienna Bioctr, Res Inst Mol Pathol, Vienna, Austria

***Article 15
with Esteller, M
Total Cites: 568
Article Title: A gene hypermethylation profile of human cancer
Authors: Esteller, M, Corn, PG, Baylin, SB, Herman, JG
Journal: CANCER RESEARCH
Volume: 61
Page: 3225-3229
Year: 2001
Addresses: 
· Johns Hopkins Comprehens Canc Ctr, Baltimore, MD, USA

***Article 16
Total Cites: 545
Article Title: Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
Authors: Kennerdell, JR, Carthew, RW
Journal: CELL
Volume: 95
Page: 1017-1026
Year: 1998
Addresses: 
· Univ Pittsburgh, Dept Biol Sci, Pittsburgh, PA, USA

***Article 17
Total Cites: 540
Article Title: Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
Authors: Volpe, TA, Kidner, C, Hall, IM, Teng, G, Grewal, SIS, Martienssen, RA
Journal: SCIENCE
Volume: 297
Page: 1833-1837
Year: 2002
Addresses: 
· Cold Spring Harbor Lab, Cold Spring Harbor, NY, USA
· Watson Sch Biol Sci, Cold Spring Harbor, NY, USA

***Article 18
Total Cites: 531
Article Title: Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
Authors: Kamath, RS, Fraser, AG, Dong, Y, Poulin, G, Durbin, R, Gotta, M, Kanapin, A, Le Bot, N, Moreno, S, Sohrmann, M, Welchman, DP, Zipperlen, P, Ahringer, J
Journal: NATURE
Volume: 421
Page: 231-237
Year: 2003
Addresses: 
· Univ Cambridge, Wellcome Trust Canc Res UK Inst, Cambridge, England
· Univ Cambridge, Dept Genet, Cambridge, England
· Wellcome Trust Sanger Inst, Cambridge, England
· EMBL, European Bioinformat Inst, Cambridge, England
· Univ Salamanca, CSIC, Ctr Invest Canc, Salamanca, Spain

***Article 19
Total Cites: 524
Article Title: Functional genomic analysis of C-elegans chromosome I by systematic RNA interference
Authors: Fraser, AG, Kamath, RS, Zipperlen, P, Martinez-campos, M, Sohrmann, M, Ahringer, J
Journal: NATURE
Volume: 408
Page: 325-330
Year: 2000
Addresses: 
· Univ Cambridge, Wellcome CRC Inst, Cambridge, England
· Sanger Ctr, Cambridge, England

***Article 20
Total Cites: 490
Article Title: A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
Authors: Sui, GC, Soohoo, C, Affar, E, Gay, F, Shi, YJ, Forrester, WC, Shi, Y
Journal: P NATL ACAD SCI USA
Volume: 99
Page: 5515-5520
Year: 2002
Addresses: 
· Harvard Univ, Sch Med, Dept Pathol, Boston, MA, USA