New Hot Paper Comment by Rudy L. Juliano

Rudy L. Juliano answers a few questions about this month's new hot paper in the field of Pharmacology & Toxicology.

From •>>July 2003

Field: Pharmacology & Toxicology
Article Title: "Signal transduction by cell adhesion receptors and the cytoskeleton: Functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members"
Authors: Juliano, RL
Journal: ANNU REV PHARMACOL TOXICOL
Volume: 42:
Page: 283-323
Year: 2002
* Univ N Carolina, Sch Med, Dept Pharmacol, Chapel Hill, NC 27599 USA.
* Univ N Carolina, Sch Med, Dept Pharmacol, Chapel Hill, NC 27599 USA.

Why do you think your paper is highly cited?

It provides a broad ranging review of the topic.

Could you summarize the significance of your paper in layman's terms?

Proteins that are involved in cell-cell or cell-matrix interactions are also important in regulating signal transduction pathways.

How long have you been involved in this research?

I have been in this area for many years. Basically, our laboratory works on the integrin family of cell-matrix adhesion receptors and how these proteins influence signaling pathways, such as the MAP kinase pathway that is critical for cell replication.

Rudy L. Juliano
Professor
Dept. of Pharmacology
University of North Carolina
Chapel Hill, NC, USA

ESI Special Topics, July 2003
Citing URL - http://www.esi-topics.com/nhp/2003/july-03-RudyLJuliano.html