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 ***Article 1
Total Cites: 2409
Article Title: POSITIONAL CLONING OF THE MOUSE OBESE GENE AND ITS HUMAN HOMOLOG
Authors: Zhang YY, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM
Journal: NATURE
Volume: 372
Page: 425
Year: 1994
Addresses:
· HOWARD HUGHES MED INST, 1230 YORK AVE, NEW YORK, NY, US
· HOWARD HUGHES MED INST, NEW YORK, NY, US
· ROCKEFELLER UNIV, NEW YORK, NY, US
***Article 2
Total Cites: 1464
Article Title: EFFECTS OF THE OBESE GENE-PRODUCT ON BODY-WEIGHT REGULATION IN OB/OB MICE
Authors: Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F
Journal: SCIENCE
Volume: 269
Page: 540
Year: 1995
Addresses:
· AMGEN INC, DEPT NEUROBIOL, 1840 DEHAVILLAND DR, THOUSAND OAKS, CA, US
· AMGEN INC, DEPT RECOVERY PROC DEV, THOUSAND OAKS, CA, US
***Article 3
Total Cites: 1371
Article Title: WEIGHT-REDUCING EFFECTS OF THE PLASMA-PROTEIN ENCODED BY THE OBESE GENE
Authors: Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM
Journal: SCIENCE
Volume: 269
Page: 543
Year: 1995
Addresses:
· ROCKEFELLER UNIV, HOWARD HUGHES MED INST, GENET MOLEC LAB, 1230 YORK AVE, NEW YORK, NY, US
· ROCKEFELLER UNIV, HOWARD HUGHES MED INST, GENET MOLEC LAB, NEW YORK, NY, US
· ROCKEFELLER UNIV, HOWARD HUGHES MED INST, MOLEC BIOPHYS LABS, NEW YORK, NY, US
· ROCKEFELLER UNIV, MASS SPECTROMETRY LAB, NEW YORK, NY, US
· COLUMBIA UNIV, DEPT STAT, NEW YORK, NY, US
· BROOKWOOD BIOMED CTR, BIRMINGHAM, AL, US
***Article 4
Total Cites: 1312
Article Title: INSULIN RESISTANCE - A MULTIFACETED SYNDROME RESPONSIBLE FOR NIDDM, OBESITY, HYPERTENSION, DYSLIPIDEMIA, AND ATHEROSCLEROTIC CARDIOVASCULAR-DISEASE
Authors: Defronzo RA, Ferrannini E
Journal: DIABETES CARE
Volume: 14
Page: 173
Year: 1991
Addresses:
· UNIV TEXAS, HLTH SCI CTR, DEPT MED, DIV DIABET, SAN ANTONIO, TX, US
· UNIV PISA, MED CLIN 2, CTR NATL RES INST CLIN PHYSIOL, METAB UNIT, I-56100 PISA, ITALY
***Article 5
Total Cites: 1167
Article Title: SERUM IMMUNOREACTIVE LEPTIN CONCENTRATIONS IN NORMAL-WEIGHT AND OBESE HUMANS
Authors: Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, Mckee LJ, Bauer TL, Caro JF
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Volume: 334
Page: 292
Year: 1996
Addresses:
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DIV ENDOCRINOL & METAB, 1025 WALNUT ST, PHILADELPHIA, PA, US
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT CLIN PHARMACOL, BIOSTAT SECT, PHILADELPHIA, PA, US
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT MED, PHILADELPHIA, PA, US
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT SURG, PHILADELPHIA, PA, US
· ELI LILLY & CO, LILLY RES LABS, INDIANAPOLIS, IN, US
***Article 6
Total Cites: 964
Article Title: INCREASING PREVALENCE OF OVERWEIGHT AMONG US ADULTS - THE NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEYS, 1960 TO 1991
Authors: Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL
Journal: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Volume: 272
Page: 205
Year: 1994
Addresses:
· 6525 BELCREST RD, ROOM 900, HYATTSVILLE, MD, US
· CTR DIS CONTROL & PREVENT, NATL CTR HLTH STAT, DIV HLTH EXAMINAT STAT, HYATTSVILLE, MD, US
***Article 7
Total Cites: 840
Article Title: LEPTIN LEVELS IN HUMAN AND RODENT - MEASUREMENT OF PLASMA LEPTIN AND OB RNA IN OBESE AND WEIGHT-REDUCED SUBJECTS
Authors: Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S, Kern PA, Friedman JM
Journal: NATURE MEDICINE
Volume: 1
Page: 1155
Year: 1995
Addresses:
· ROCKEFELLER UNIV, MOLEC GENET LAB, 1230 YORK AVE, NEW YORK, NY, US
· ROCKEFELLER UNIV, MOLEC GENET LAB, NEW YORK, NY, US
· NIDDKD, CLIN DIABET & NUTR SECT, PHOENIX, AZ, US
· BROOKWOOD BIOMED ACC, BIRMINGHAM, AL, US
· CEDARS SINAI MED CTR, LOS ANGELES, CA, US
· ROCKEFELLER UNIV, HOWARD HUGHES MED INST, NEW YORK, NY, US
***Article 8
Total Cites: 694
Article Title: THE ROLE OF NEUROPEPTIDE-Y IN THE ANTIOBESITY ACTION OF THE OBESE GENE-PRODUCT
Authors: Stephens TW, Basinski M, Bristow PK, Buevalleskey JM, Burgett SG, Craft L, Hale J, Hoffmann J, Hsiung HM, Kriauciunas A, Mackellar W, Rosteck PR, Schoner B, Smith D, Tinsley FC, Zhang XY
Journal: NATURE
Volume: 377
Page: 530
Year: 1995
Addresses:
· ELI LILLY & CO, LILLY RES LABS, DIV ENDOCRINE RES, INDIANAPOLIS, IN, US
· ELI LILLY & CO, LILLY RES LABS, DIV TECHNOL CORE, INDIANAPOLIS, IN, US
***Article 9
Total Cites: 516
Article Title: TRANSIENT INCREASE IN OBESE GENE-EXPRESSION AFTER FOOD-INTAKE OR INSULIN ADMINISTRATION
Authors: Saladin R, Devos P, Guerremillo M, Leturque A, Girard J, Staels B, Auwerx J
Journal: NATURE
Volume: 377
Page: 527
Year: 1995
Addresses:
· INST PASTEUR, BIOL REGULAT CHEZ EUCARYOTES LAB, INSERM, U325, F-59019 LILLE, FRANCE
· INST BIOMED CORDELIERS, INSERM, U177, F-75006 PARIS, FRANCE
· CNRS, UPR 1511, CEREMOD, F-92190 MEUDON, FRANCE
***Article 10
Total Cites: 448
Article Title: UNCOUPLING PROTEIN-2 - A NOVEL GENE LINKED TO OBESITY AND HYPERINSULINEMIA
Authors: Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levimeyrueis C, Bouillaud F, Seldin MF, Surwit RS, Ricquier D, Warden CH
Journal: NATURE GENETICS
Volume: 15
Page: 269
Year: 1997
Addresses:
· UNIV CALIF DAVIS, DEPT PEDIAT, ROWE PROGRAM GENET, DAVIS, CA, US
· UNIV CALIF DAVIS, DEPT PEDIAT, ROWE PROGRAM GENET, DAVIS, CA, US
· UNIV CALIF DAVIS, DEPT BIOL CHEM, DAVIS, CA, US
· UNIV CALIF DAVIS, DEPT MED, DAVIS, CA, US
· CNRS, CEREMOD, F-92190 MEUDON, FRANCE
· DUKE UNIV, MED CTR, DEPT PSYCHIAT & BEHAV SCI, SARAH STEDMAN NUTR CTR, DURHAM, NC, US
· DUKE UNIV, MED CTR, DEPT PHARMACOL, DURHAM, NC, US
***Article 11
Total Cites: 438
Article Title: CONGENITAL LEPTIN DEFICIENCY IS ASSOCIATED WITH SEVERE EARLY-ONSET OBESITY IN HUMANS
Authors: Montague CT, Farooqi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AR, Barnett AH, Prins JB, Orahilly S
Journal: NATURE
Volume: 387
Page: 903
Year: 1997
Addresses:
· UNIV CAMBRIDGE, ADDENBROOKES HOSP, DEPT MED, HILLS RD, CAMBRIDGE CB2 2QR, ENGLAND
· UNIV CAMBRIDGE, ADDENBROOKES HOSP, DEPT MED, CAMBRIDGE CB2 2QR, ENGLAND
· UNIV CAMBRIDGE, ADDENBROOKES HOSP, DEPT CLIN BIOCHEM, CAMBRIDGE CB2 2QR, ENGLAND
· UNIV CAMBRIDGE, ADDENBROOKES HOSP, DEPT COMMUNITY MED, CAMBRIDGE CB2 2QR, ENGLAND
· GUYS HOSP, S THAMES REG GENET CTR E, LONDON SE1 9RT, ENGLAND
· CHURCHILL HOSP, OXFORD REG GENET SERV, OXFORD OX3 7LJ, ENGLAND
· WYCOMBE GEN HOSP, HIGH WYCOMBE B9 5SS, ENGLAND
· UNIV BIRMINGHAM, DEPT MED, BIRMINGHAM B9 5SS, ENGLAND
· BIRMINGHAM HEARTLANDS HOSP, BIRMINGHAM B9 5SS, ENGLAND
***Article 12
Total Cites: 435
Article Title: CORRECTION OF THE STERILITY DEFECT IN HOMOZYGOUS OBESE FEMALE MICE BY TREATMENT WITH THE HUMAN RECOMBINANT LEPTIN
Authors: Chehab FE, Lim ME, Lu RH
Journal: NATURE GENETICS
Volume: 12
Page: 318
Year: 1996
Addresses:
· UNIV CALIF SAN FRANCISCO, DEPT LAB MED, SAN FRANCISCO, CA, US
***Article 13
Total Cites: 372
Article Title: LEPTIN - THE TALE OF AN OBESITY GENE
Authors: Caro JF, Sinha MK, Kolaczynski JW, Zhang PL, Considine RV
Journal: DIABETES
Volume: 45
Page: 1455
Year: 1996
Addresses:
· LILLY CORP CTR, LILLY RES LABS, DIABET RES & CLIN INVEST, INDIANAPOLIS, IN, US
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT MED, PHILADELPHIA, PA, US
***Article 14
Total Cites: 355
Article Title: TARGETED DISRUPTION OF THE MELANOCORTIN-4 RECEPTOR RESULTS IN OBESITY IN MICE
Authors: Huszar D, Lynch CA, Fairchildhuntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F
Journal: CELL
Volume: 88
Page: 131
Year: 1997
Addresses:
· MILLENNIUM PHARMACEUT INC, 640 MEM DR, CAMBRIDGE, MA, US
· OREGON HLTH SCI UNIV, VOLLUM INST ADV BIOMED RES, PORTLAND, OR, US
· OREGON HLTH SCI UNIV, DEPT PEDIAT, PORTLAND, OR, US
· HOFFMANN LA ROCHE INC, DEPT METAB DIS, NUTLEY, NJ, US
***Article 15
Total Cites: 343
Article Title: ROLE OF MELANOCORTINERGIC NEURONS IN FEEDING AND THE AGOUTI OBESITY SYNDROME
Authors: Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD
Journal: NATURE
Volume: 385
Page: 165
Year: 1997
Addresses:
· OREGON HLTH SCI UNIV, VOLLUM INST ADV BIOMED RES, 3181 SW SAM JACKSON PK RD, PORTLAND, OR, US
· OREGON HLTH SCI UNIV, VOLLUM INST ADV BIOMED RES, PORTLAND, OR, US
· OREGON HLTH SCI UNIV, DEPT PEDIAT, PORTLAND, OR, US
· UNIV ARIZONA, DEPT CHEM, TUCSON, AZ, US
***Article 16
Total Cites: 336
Article Title: IMPROVEMENT IN GLUCOSE-TOLERANCE AND INSULIN-RESISTANCE IN OBESE SUBJECTS TREATED WITH TROGLITAZONE
Authors: Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Volume: 331
Page: 1188
Year: 1994
Addresses:
· UNIV CALIF SAN DIEGO, DEPT MED, DIV ENDOCRINOL & METAB, 9111-G, LA JOLLA, CA, US
· UNIV CALIF SAN DIEGO, DEPT MED, DIV ENDOCRINOL & METAB, LA JOLLA, CA, US
· VET AFFAIRS MED CTR, SAN DIEGO, CA, US
***Article 17
Total Cites: 321
Article Title: OVEREXPRESSION OF THE OBESE %OB< GENE IN ADIPOSE-TISSUE OF HUMAN OBESE SUBJECTS
Authors: Lonnqvist F, Arner P, Nordfors L, Schalling M
Journal: NATURE MEDICINE
Volume: 1
Page: 950
Year: 1995
Addresses:
· KAROLINSKA HOSP, DEPT MOLEC MED, NEUROGENET UNIT, KAROLINSKA INST, S-17176 STOCKHOLM, SWEDEN
· HUDDINGE UNIV HOSP, DEPT MED, KAROLINSKA INST, S-14186 STOCKHOLM, SWEDEN
· HUDDINGE UNIV HOSP, RES CTR, S-14186 STOCKHOLM, SWEDEN
***Article 18
Total Cites: 318
Article Title: EVIDENCE AGAINST EITHER A PREMATURE STOP CODON OR THE ABSENCE OF OBESE GENE MESSENGER-RNA IN HUMAN OBESITY
Authors: Considine RV, Considine EL, Williams CJ, Nyce MR, Magosin SA, Bauer TL, Rosato EL, Colberg J, Caro JF
Journal: JOURNAL OF CLINICAL INVESTIGATION
Volume: 95
Page: 2986
Year: 1995
Addresses:
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT MED, DIV ENDOCRINOL & METAB, PHILADELPHIA, PA, US
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT BIOCHEM & MOLEC BIOL, PHILADELPHIA, PA, US
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT SURG, PHILADELPHIA, PA, US
***Article 19
Total Cites: 314
Article Title: INCREASED ADIPOSE-TISSUE EXPRESSION OF TUMOR-NECROSIS-FACTOR-ALPHA IN HUMAN OBESITY AND INSULIN-RESISTANCE
Authors: Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM
Journal: JOURNAL OF CLINICAL INVESTIGATION
Volume: 95
Page: 2409
Year: 1995
Addresses:
· DANA FARBER CANC INST, 44 BINNEY ST, BOSTON, MA, US
· DANA FARBER CANC INST, BOSTON, MA, US
· HARVARD UNIV, SCH MED, DEPT CELL BIOL, BOSTON, MA, US
· HUDDINGE UNIV HOSP, KAROLINSKA INST, DEPT MED, S-14186 HUDDINGE, SWEDEN
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT MED, PHILADELPHIA, PA, US
· MED COLL WISCONSIN, DEPT MED, MADISON, WI, US
***Article 20
Total Cites: 314
Article Title: RELATION OF CENTRAL OBESITY AND INSULIN RESISTANCE WITH HIGH DIABETES PREVALENCE AND CARDIOVASCULAR RISK IN SOUTH ASIANS
Authors: Mckeigue PM, Shah B, Marmot MG
Journal: LANCET
Volume: 337
Page: 382
Year: 1991
Addresses:
· UNIV COLL & MIDDLESEX SCH MED, DEPT COMMUNITY MED, LONDON, ENGLAND
***Article 21
Total Cites: 307
Article Title: OVERWEIGHT PREVALENCE AND TRENDS FOR CHILDREN AND ADOLESCENTS - THE NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEYS, 1963 TO 1991
Authors: Troiano RP, Flegal KM, Kuczmarski RJ, Campbell SM, Johnson CL
Journal: ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE
Volume: 149
Page: 1085
Year: 1995
Addresses:
· NATL CTR HLTH STAT, CTR DIS CONTROL & PREVENT, 6525 BELCREST RD, ROOM 900, HYATTSVILLE, MD, US
***Article 22
by Flier
JS
Total Cites: 305
Article Title: ADIPOGENESIS AND OBESITY - ROUNDING OUT THE BIG PICTURE
Authors: Spiegelman BM,
Flier
JS
Journal: CELL
Volume: 87
Page: 377
Year: 1996
Addresses:
· HARVARD UNIV, SCH MED, DANA FARBER CANC INST, 44 BINNEY ST, BOSTON, MA, US
· HARVARD UNIV, SCH MED, DEPT CELL BIOL, BOSTON, MA, US
· HARVARD UNIV, SCH MED, DIV ENDOCRINOL, BETH ISRAEL DEACONESS MED CTR, BOSTON, MA, US
· HARVARD UNIV, SCH MED, DEPT MED, BOSTON, MA, US
***Article 23
by Dietz WH
Total Cites: 302
Article Title: LONG-TERM MORBIDITY AND MORTALITY OF OVERWEIGHT ADOLESCENTS - A FOLLOW-UP OF THE HARVARD GROWTH STUDY OF 1922 TO 1935
Authors: Must A, Jacques PF, Dallal GE, Bajema CJ, Dietz WH
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Volume: 327
Page: 1350
Year: 1992
Addresses:
· TUFTS UNIV, USDA, HUMAN NUTR RES CTR, EPIDEMIOL PROGRAM, BOSTON, MA, US
· GRAND VALLEY STATE UNIV, ALLENDALE, MI, US
· TUFTS UNIV, USDA, HUMAN NUTR RES CTR, DIV BIOSTAT, BOSTON, MA, US
· NEW ENGLAND MED CTR, BOSTON, MA, US
***Article 24
Total Cites: 280
Article Title: A MUTATION IN THE HUMAN LEPTIN RECEPTOR GENE CAUSES OBESITY AND PITUITARY DYSFUNCTION
Authors: Clement K, Vaisse C, Lahlou N, Cabrol S, Pelloux V, Cassuto D, Gourmelen M, Dina C, Chambaz J, Lacorte JM, Basdevant A, Bougneres P, Lebouc Y, Froguel P, Guygrand B
Journal: NATURE
Volume: 392
Page: 398
Year: 1998
Addresses:
· HOP HOTEL DIEU, LAB NUTR, PL PARVIS NOTRE DAME, F-75004 PARIS, FRANCE
· HOP HOTEL DIEU, LAB NUTR, F-75004 PARIS, FRANCE
· HOP HOTEL DIEU, SERV MED & NUTR, F-75004 PARIS, FRANCE
· INST PASTEUR, INST BIOL, CNRS, EP10, F-59000 LILLE, FRANCE
· HOP ST VINCENT DE PAUL, INSERM, U342, F-75674 PARIS, FRANCE
· SERV ENDOCRINOL DIABETE ENFANT, F-75014 PARIS, FRANCE
· HOP ENFANT ARMAND TROUSSEU, F-75012 PARIS, FRANCE
· INSERM, CJF 9508, F-75005 PARIS, FRANCE
***Article 25
Total Cites: 277
Article Title: NOCTURNAL RISE OF LEPTIN IN LEAN, OBESE, AND NON-INSULIN-DEPENDENT DIABETES-MELLITUS SUBJECTS
Authors: Sinha MK, Ohannesian JP, Heiman ML, Kriauciunas A, Stephens TW, Magosin S, Marco C, Caro JF
Journal: JOURNAL OF CLINICAL INVESTIGATION
Volume: 97
Page: 1344
Year: 1996
Addresses:
· THOMAS JEFFERSON UNIV, JEFFERSON MED COLL, DEPT MED, DIV ENDOCRINOL & METAB, PHILADELPHIA, PA, US
· ELI LILLY & CO, LILLY RES LABS, INDIANAPOLIS, IN, US
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