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TOP PAPERS published in the last
two-year period
(sixth bimonthly; 2005-December
31,
2006)
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 ***Article 1
Total Cites: 108
Article Title: Common LRRK2 mutation in idiopathic
Parkinson's disease
Authors: Gilks, WP, Abou-sleiman, PM, Gandhi, S, Jain,
S, Singleton, A, Lees, AJ, Shaw, K, Bhatia, KP, Bonifati,
V, Quinn, NP, Lynch, J, Healy, DG, Holton, JL, Revesz,
T, Wood, NW
Journal: LANCET
Volume: 365
Page: 415-416
Year: 2005
Addresses:
· Inst Neurol, Dept Mol Neurosci, London, England
· Inst Neurol, Dept Motor Neurosci, London, England
· Natl Hosp Neurol & Neurosurg, London, England
· NIA, Neurogenet Lab, NIH, Bethesda, MD, USA
· Erasmus Univ, Dept Clin Genet, Rotterdam, Netherlands
· Reta Lila Weston Inst Neurol Studies, London, England
· Inst Neurol, Dept Mol Neurosci, Queen Sq, London,
England
***Article 2
Total Cites: 96
Article Title: A frequent LRRK2 gene mutation associated
with autosomal dominant Parkinson's disease
Authors: Di Fonzo, A, Rohe, CF, Ferreira, RJ, Chien, HF,
Vacca, L, Stocchi, F, Guedes, L, Fabrizio, E, Manfredi,
M, Vanacore, N, Goldwurm, S, Breedveld, G, Sampaio, C,
Meco, G, Barbosa, E, Oostra, BA, Bonifati, V, Italian
Parkinson Genetics Network
Journal: LANCET
Volume: 365
Page: 412-415
Year: 2005
Addresses:
· Erasmus MC Rotterdam, Dept Clin Genet, Rotterdam,
Netherlands
· Univ Milan, IRCCS Osped Maggiore Policlin, Ctr Dino
Ferrari, Dept Neurol Sci, Milan, Italy
· Inst Mol Med, Neurol Clin Res Unit, Lisbon, Portugal
· Univ Sao Paulo, Dept Neurol, Sao Paulo, Brazil
· Univ Roma La Sapienza, Dept Neurol Sci, Rome, Italy
· Natl Inst Hlth, Natl Ctr Epidemiol, Rome, Italy
· Ist Clin Perfezionamento, Parkinson Inst, Milan, Italy
· Erasmus MC Rotterdam, Dept Clin Genet, POB 1738,
Rotterdam, Netherlands
***Article 3
Total Cites: 91
Article Title: Genetic screening for a single common
LRRK2 mutation in familial Parkinson's disease
Authors: Nichols, WC, Pankratz, N, Hernandez, D,
Paisan-ruiz, C, Jain, S, Halter, CA, Michaels, VE, Reed,
T, Rudolph, A, Shults, CW, Singleton, A, Foroud, T,
Parkinson Study Grp PROGENI Invest
Journal: LANCET
Volume: 365
Page: 410-412
Year: 2005
Addresses:
· Cincinnati Childrens Hosp Med Ctr, Div Human Genet,
Cincinnati, OH, USA
· Indiana Univ, Med Ctr, Dept Med & Mol Genet,
Indianapolis, IN, USA
· NIA, Mol Genet Unit, NIH, Bethesda, MD, USA
· CSIC, Dept Genom & Proteom, Inst Biomed Valencia,
Unitat Genet Mol, Valencia, Spain
· Inst Neurol, Dept Mol Neurosci, London, England
· Univ Rochester, Dept Neurol, Rochester, NY, USA
· Univ Calif, Dept Neurosci, La Jolla, CA, USA
· Vet Affairs San Diego Healthcare Syst, San Diego, CA,
USA
· Cincinnati Childrens Hosp Med Ctr, Div Human Genet,
3333 Burnet Ave,1469 TCHRF, Cincinnati, OH, USA
***Article 4
Total Cites: 79
Article Title: Identification of a novel LRRK2 mutation
linked to autosomal dominant parkinsonism: Evidence of a
common founder across European populations
Authors: Kachergus, J, Mata, IF, Hulihan, M, Taylor, JP,
Lincoln, S, Aasly, J, Gibson, JM, Ross, OA, Lynch, T,
Wiley, J, Payami, H, Nutt, J, Maraganore, DM, Czyzewski,
K, Styczynska, M, Wszolek, ZK, Farrer, MJ, Toft, M
Journal: AM J HUM GENET
Volume: 76
Page: 672-680
Year: 2005
Addresses:
· Mayo Clin, Dept Neurosci, Jacksonville, FL, USA
· Mayo Clin, Dept Neurol, Jacksonville, FL, USA
· St Olavs Hosp, Dept Neurol, Trondheim, Norway
· Norwegian Univ Sci & Technol, Dept Neurosci, Trondheim,
Norway
· Royal Victoria Hosp, Dept Neurol, Belfast, North
Ireland
· Queens Univ Belfast, Sch Biol & Biochem, Belfast,
North Ireland
· Mater Misericordiae Univ Hosp, Dept Neurol, Dublin,
Ireland
· Conway Inst Biomol & Biomed Res, Dublin, Ireland
· New York State Dept Hlth, Wadsworth Ctr Labs & Res,
Albany, NY, USA
· Oregon Hlth Sci Univ, Dept Neurol, Portland, OR, USA
· Mayo Clin, Dept Neurol, Rochester, MN, USA
· Polish Acad Sci, Med Res Ctr, Dept Neurodegenerat
Disorders, Warsaw, Poland
· Minist Spraw Wewnetrznych & Adm Hosp, Dept Neurol,
Warsaw, Poland
· Mayo Clin, Dept Neurosci, Birdsall Bldg,4500 San Pablo
Rd, Jacksonville, FL, USA
***Article 5
Total Cites: 60
Article Title: Molecular pathophysiology of Parkinson's
disease
Authors: Moore, DJ, West, AB, Dawson, VL, Dawson, TM
Journal: ANNUAL REVIEW OF NEUROSCIENCE
Volume: 28
Page: 57-87
Year: 2005
Addresses:
· Johns Hopkins Univ, Sch Med, Inst Cell Engn,
Baltimore, MD, USA
· Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore,
MD, USA
· Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore,
MD, USA
· Johns Hopkins Univ, Sch Med, Dept Physiol, Baltimore,
MD, USA
***Article 6
Total Cites: 54
Article Title: Dopaminergic neurons generated from
monkey embryonic stem cells function in a Parkinson
primate model
Authors: Takagi, Y, Takahashi, J, Saiki, H, Morizane, A,
Hayashi, T, Kishi, Y, Fukuda, H, Okamoto, Y, Koyanagi,
M, Ideguchi, M, Hayashi, H, Imazato, T, Kawasaki, H,
Suemori, H, Omachi, S, Iida, H, Itoh, N, Nakatsuji, N,
Sasai, Y, Hashimoto, N
Journal: JOURNAL OF CLINICAL INVESTIGATION
Volume: 115
Page: 102-109
Year: 2005
Addresses:
· Kyoto Univ, Grad Sch Med, Dept Neurosurg, Sakyo Ku,
Kyoto, Japan
· RIKEN, Ctr Dev Biol, Organogenesis & Neurogenesis Grp,
Kobe, Japan
· Kyoto Univ, Grad Sch Med, Dept Neurol, Kyoto, Japan
· Natl Cardiovasc Ctr, Dept Expt Radiol, Osaka, Japan
· Kyoto Univ, Inst Frontier Med Sci, Dept Dev &
Differentiat, Kyoto, Japan
· Kyoto Univ, Dept Med Embryol & Neurobiol, Kyoto, Japan
· Kyoto Univ, Grad Sch Pharmaceut Sci, Dept Biochem
Genet, Kyoto, Japan
***Article 7
Total Cites: 46
Article Title: The biochemistry of Parkinson's disease
Authors: Cookson, MR
Journal: ANNUAL REVIEW OF BIOCHEMISTRY
Volume: 74
Page: 29-52
Year: 2005
Addresses:
· NIA, Neurogenet Lab, Cell Biol Sect, Bethesda, MD, USA
***Article 8
Total Cites: 44
Article Title: Parkinson-like syndrome induced by
continuous MPTP infusion: Convergent roles of the
ubiquitin-proteasome system and alpha-synuclein
Authors: Fornai, F, Schluter, OM, Lenzi, P, Gesi, M,
Ruffoli, R, Ferrucci, M, Lazzeri, G, Busceti, CL,
Pontarelli, F, Battaglia, G, Pellegrini, A, Nicoletti,
F, Ruggieri, S, Paparelli, A, Sudhof, TC
Journal: P NATL ACAD SCI USA
Volume: 102
Page: 3413-3418
Year: 2005
Addresses:
· Univ Pisa, Dept Human Morphol & Appl Biol, Pisa, Italy
· Neuromed Pozzilli IS, Inst Neurol Mediterraneo, Ist
Ric & Cura Carattere sci, Lab Neurobiol Movement
Disorders, Pozzilli, Italy
· Max Planck Inst Expt Med, Gottingen, Germany
· Univ Roma La Sapienza, Dept Neurol Sci, Rome, Italy
· Univ Texas, SW Med Ctr, Howard Hughes Med Inst, Ctr
Basic Neurosci, Dallas, TX, USA
***Article 9
Total Cites: 40
Article Title: alpha-Synuclein phosphorylation controls
neurotoxicity and inclusion formation in a Drosophila
model of Parkinson disease
Authors: Chen, L, Feany, MB
Journal: NATURE NEUROSCIENCE
Volume: 8
Page: 657-663
Year: 2005
Addresses:
· Brigham & Womens Hosp, Dept Pathol, Boston, MA, USA
· Harvard Univ, Sch Med, Boston, MA, USA
· Brigham & Womens Hosp, Dept Pathol, 75 Francis St,
Boston, MA, USA
***Article 10
Total Cites: 38
Article Title: High-resolution whole-genome association
study of Parkinson disease
Authors: Maraganore, DM, de Andrade, M, Lesnick, TG,
Strain, KJ, Farrer, MJ, Rocca, WA, Pant, PVK, Frazer,
KA, Cox, DR, Ballinger, DG
Journal: AM J HUM GENET
Volume: 77
Page: 685-693
Year: 2005
Addresses:
· Perlegen Sci Inc, Mountain View, CA, USA
· Mayo Clin, Coll Med, Dept Neurol, Rochester, MN, USA
· Mayo Clin, Coll Med, Dept Hlth Sci Res, Rochester, MN,
USA
· Mayo Clin, Coll Med, Dept Neurosci, Jacksonville, FL,
USA
· Perlegen Sci Inc, 2021 Stierlin Court, Mountain View,
CA, USA
***Article 11
Total Cites: 38
Article Title: A randomized placebo-controlled trial of
rasagiline in levodopa-treated patients with Parkinson
disease and motor fluctuations - The PRESTO study
Authors: Schwid, SR, Shoulson, I, Stern, M, Oakes, D,
Kieburtz, K, Fahn, S, Blinclauer, K, Demarcaida, A,
Elmer, L, Davis, K, Fazzini, E, Chin, L, Scott, B,
Wilcox, C, Colcher, A, Reichwein, S, Hauser, R, Gauger,
L, Leehey, M, Lewitt, P, Kaminski, P, Harrison, M,
Rost-ruffner, E, Racette, B, Frei, K, Luong, N, Pahwa,
R, Dicarlo, J, Kawai, C, Jennings, D, Caplan, K, Fink,
JS, Novak, P, Thomas, CA, Chouinard, S, Beauvais, C,
Tabbal, S, Patterson, J, Fernandez, H, Bertoni, JM,
Skrypnik, L, Panisset, M, Fortin, MJ, Molho, E, Nash, J,
Dalvi, A, Schwiterman, D, Goetz, C, Janko, K, Mendis, T,
Mahtat, D, Gray, P, Camicioli, R, King, P, Wojcieszek,
J, Kumar, R, Judd, D, Margolin, D, Margolin, JJ, Clem,
K, Gordon, P, Marshall, F, Berry, D, Rottenberg, D,
Hansen, J, Gordon, MF, Hassan, M, Keltonic, P,
Hermanowicz, N, Niswonger, S, Jog, M, Horn, C, Shulman,
L, Cines, M, Suchowersky, O, Furtado, S, Derwent, L,
Samanta, J, Williamson, K, Ramos, CS, Berrios, L, Roque,
S, Sutton, J, Young, J, Waters, C, Benabou, R, Singer,
C, Koller, W, Martin, D, Sethi, K, Carpenter, J, Rao, J,
Cook, M, Feigin, A, Cox, M, Riley, D, Calabrese, V,
Standaert, D, Tennis, M, Whetteckey, J, Wulbrecht, B,
Rajput, A, Golbe, L, Caputo, D, Freeman, A, Mcginn, L,
Subramanian, T, Ajax, T, Aminoff, M, Hevezi, J, So, J,
Bausch, J, Brocht, A, Chadwick, C, Daigneault, S, Eberly,
S, Goldstein, M, Hodgeman, K, Irvine, C, Johnsen, D,
Kamp, C, Kamp, D, Lutz, M, Plumb, S, Shinaman, A,
Weaver, C, Tariot, P, Cox, C, Prisant, LM, Rodnitzky, R,
Oren, S, Levy, R, Eyal, E, Goren, T, Friedman, S,
Salzman, P, Schwartz, B, Lundbeck, H, Forrest, M,
Parkinson Study Grp
Journal: ARCH NEUROL-CHICAGO
Volume: 62
Page: 241-248
Year: 2005
Addresses:
***Article 12
Total Cites: 38
Article Title: Parkinson's disease-associated mutations
in leucine-rich repeat kinase 2 augment kinase activity
Authors: West, AB, Moore, DJ, Biskup, S, Bugayenko, A,
Smith, WW, Ross, CA, Dawson, VL, Dawson, TM
Journal: P NATL ACAD SCI USA
Volume: 102
Page: 16842-16847
Year: 2005
Addresses:
· Johns Hopkins Univ, Sch Med, Inst Cell Engn,
Baltimore, MD, USA
· Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore,
MD, USA
· Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore,
MD, USA
· Johns Hopkins Univ, Sch Med, Dept Physiol, Baltimore,
MD, USA
· Johns Hopkins Univ, Sch Med, Dept Psychiat, Baltimore,
MD, USA
· Johns Hopkins Univ, Sch Med, Div Neurobiol, Baltimore,
MD, USA
· 733 N Broadway,Suite 731,Broadway Res Bldg, Baltimore,
MD, USA
***Article 13
Total Cites: 37
Article Title: Nigrostriatal dopaminergic deficits and
hypokinesia caused by inactivation of the familial
Parkinsonism-linked gene DJ-1
Authors: Goldberg, MS, Pisani, A, Haburcak, M, Vortherms,
TA, Kitada, T, Costa, C, Tong, Y, Martella, G, Tscherter,
A, Martins, A, Bernardi, G, Roth, BL, Pothos, EN,
Calabresi, P, Shen, J
Journal: NEURON
Volume: 45
Page: 489-496
Year: 2005
Addresses:
· Harvard Univ, Sch Med, Ctr Neurol Dis, Brigham &
Womens Hosp,Program Neurosci, Boston, MA, USA
· Univ Roma Tor Vergata, Dept Neurosci, Rome, Italy
· IRCCS, Fondaz Santa Lucia, Rome, Italy
· Tufts Univ, Sch Med, Dept Pharmacol & Expt Therapeut,
Boston, MA, USA
· Case Western Reserve Univ, Sch Med, Dept Biochem
Psychiat & Neurosci, Cleveland, OH, USA
***Article 14
Total Cites: 34
Article Title: Rasagiline as an adjunct to levodopa in
patients with Parkinson's disease and motor fluctuations
(LARGO, Lasting effect in Adjunct therapy with
Rasagiline Given Once daily, study): a randomised,
double-blind, parallel-group trial
Authors: Rascol, O, Brooks, DJ, Melamed, E, Oertel, W,
Poewe, W, Stocchi, F, Tolosa, E, Largo Study Grp
Journal: LANCET
Volume: 365
Page: 947-954
Year: 2005
Addresses:
· Univ Hosp, Fac Med, Dept Clin Pharmacol, Clin Invest
Ctr, Toulouse, France
· Hammersmith Hosp, Imperial Coll, Fac Med, Div Neurosci,
London, England
· Tel Aviv Univ, Sackler Sch Med, Rabin Med Ctr, Dept
Neurol, Tel Aviv, Israel
· Univ Marburg, Ctr Nervous Dis, Marburg, Germany
· Innsbruck Univ, Dept Neurol, Innsbruck, Austria
· IRCCS Neuromed, Inst Neurol, Pozzilli, Italy
· Univ Barcelona, IDIBAPS, Hosp Clin, Inst Malalties
Sistema Nervios,Neurol Serv, Barcelona, Spain
***Article 15
Total Cites: 34
Article Title: Bilateral deep brain stimulation in
Parkinson's disease: a multicentre study with 4 years
follow-up
Authors: Rodriguez-oroz, MC, Obeso, JA, Lang, AE, Houeto,
JL, Pollak, P, Rehncrona, S, Kulisevsky, J, Albanese, A,
Volkmann, J, Hariz, MI, Quinn, NP, Speelman, JD, Guridi,
J, Zamarbide, I, Gironell, A, Molet, J, Pascual-sedano,
B, Pidoux, B, Bonnet, AM, Agid, Y, Xie, J, Benabid, AL,
Lozano, AM, Saint-cyr, J, Romito, L, Contarino, MF,
Scerrati, M, Fraix, V, Van Blercom, N
Journal: BRAIN
Volume: 128
Page: 2240-2249
Year: 2005
Addresses:
· Clin Univ, Fac Med, Dept Neurol & Neurosurg, Pamplona,
Spain
· Univ Navarra, Sch Med, Pamplona, Spain
· CIMA, Pamplona, Spain
· Univ Toronto, Toronto Western Hosp, Div Neurol,
Movement Disorders Clin, Toronto, Canada
· Grp Hosp Pitie Salpetriere, Paris, France
· Univ Hosp Grenoble, Serv Neurol, Grenoble, France
· Univ Lund Hosp, Neurosurg Serv, Lund, Sweden
· Hosp Sant Pau, Dept Neurol, Barcelona, Spain
· Univ Cattolica, Milan, Italy
· Univ Kiel, Neurol Klin, Kiel, Germany
· Inst Neurol, London, England
· Univ Amsterdam, Acad Med Ctr, Dept Neurol, Amsterdam,
Netherlands
· Univ Cattolica Sacro Cuore, Dept Neurosci, Rome, Italy
· Clin Univ, Fac Med, Dept Neurol & Neurosurg, Avenida
Pio 12,36, Pamplona, Spain
***Article 16
Total Cites: 31
Article Title: LRRK2 mutations in Parkinson disease
Authors: Farrer, M, Stone, J, Mata, IF, Lincoln, S,
Kachergus, J, Hulihan, M, Strain, KJ, Maraganore, DM
Journal: NEUROLOGY
Volume: 65
Page: 738-740
Year: 2005
Addresses:
· Mayo Clin, Coll Med, Dept Neurosci, Jacksonville, FL,
USA
· Mayo Clin, Coll Med, Dept Hlth Sci Res, Rochester, MN,
USA
· Mayo Clin, Coll Med, Dept Neurol, Rochester, MN, USA
· Mayo Clin, Coll Med, Dept Neurosci, Birdsall Bldg,4500
San Pablo Rd, Jacksonville, FL, USA
***Article 17
Total Cites: 31
Article Title: Genetics of Parkinson's disease
Authors: Gasser, T
Journal: CURRENT OPINION IN NEUROLOGY
Volume: 18
Page: 363-369
Year: 2005
Addresses:
· Univ Tubingen, Dept Neurodegenerat Dis, Hertie Inst
Clin Brain Res, Tubingen, Germany
· Univ Tubingen, Dept Neurodegenerat Dis, Hertie Inst
Clin Brain Res, Hoppe Seyler Str 3, Tubingen, Germany
***Article 18
Total Cites: 31
Article Title: Improvement of bilateral motor functions
in patients with Parkinson disease through the
unilateral intraputaminal infusion of glial cell
line-derived neurotrophic factor
Authors: Slevin, JT, Gerhardt, GA, Smith, CD, Gash, DM,
Kryscio, R, Young, B
Journal: JOURNAL OF NEUROSURGERY
Volume: 102
Page: 216-222
Year: 2005
Addresses:
· Univ Kentucky, Albert B Chandler Med Ctr, Dept Anat &
Neurobiol, Lexington, KY, USA
· Univ Kentucky, Albert B Chandler Med Ctr, Dept Neurol,
Lexington, KY, USA
· Univ Kentucky, Albert B Chandler Med Ctr, Dept Stat &
Publ Hlth, Lexington, KY, USA
· Univ Kentucky, Albert B Chandler Med Ctr, Dept
Neurosurg, Lexington, KY, USA
· Univ Kentucky, Albert B Chandler Med Ctr, Morris K
Udall Parkinsons Dis Res Ctr Excellence, Lexington, KY,
USA
· Dept Vet Affairs Med Ctr, Neurol Serv, Lexington, KY,
USA
· Univ Kentucky, Ctr Med, Kentucky Clin, Dept Neurol,
Lexington, KY, USA
***Article 19
Total Cites: 29
Article Title: Pathological gambling caused by drugs
used to treat Parkinson disease
Authors: Dodd, ML, Klos, KJ, Bower, JH, Geda, YE,
Josephs, KA, Ahlskog, JE
Journal: ARCH NEUROL-CHICAGO
Volume: 62
Page: 1377-1381
Year: 2005
Addresses:
· Mayo Clin, Dept Psychiat, Rochester, MN, USA
· Mayo Clin, Dept Psychol, Rochester, MN, USA
· Mayo Clin, Dept Neurol, Rochester, MN, USA
· Mayo Clin & Mayo Fdn, Dept Psychiat & Psychol, 200 1st
St SW, Rochester, MN, USA
***Article 20
Total Cites: 28
Article Title: Clinical features of LRRK2-associated
Parkinson's disease in Central Norway
Authors: Aasly, JO, Toft, M, Fernandez-mata, I,
Kachergus, J, Hulihan, M, White, LR, Farrer, M
Journal: ANNALS OF NEUROLOGY
Volume: 57
Page: 762-765
Year: 2005
Addresses:
· St Olavs Hosp, Dept Neurol, Trondheim, Norway
· Mayo Clin, Coll Med, Dept Neurosci, Jacksonville, FL,
USA
· Norwegian Univ Sci & Technol, Dept Neurosci, Trondheim,
Norway
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