A number of themes emerge in the top 25 paper list for schizophrenia. Perhaps most prominent are papers dealing with various drug treatments, including the two most-cited papers. A second dominant theme is the role of receptor dysfunction in the disease, and in particular, the dopamine receptor. A third area of note is the study of structural abnormalities in the brains of schizophrenics, including abnormalities in cerebral blood flow as shown by magnetic resonance imaging. There are also a few papers dealing with the course of the disease and impairments in cognitive function that can occur.
Methodology
To construct this database, papers were extracted based on title- and author-supplied keywords for schizophrenia. The keywords used were as follows: acute schizophrenia, catatonic schizophrenia, childhood schizophrenia, childhood-onset schizophrenia, chronic schizophrenia, first-episode schizophrenia, late-onset schizophrenia, negative schizophrenia, paranoid schizophrenia, refractory schizophrenia, schizophrenia, treatment-resistant schizophrenia, chronic-schizophrenia, and schizophrenias.
The baseline time span for this database was 1981-1999. The resulting database contained 19,506 papers; 24,088 authors; 101 countries; 1,139 journals; and 5,514 organizations.
Rankings
Once the database was in place, it was used to generate the lists of top 25 papers, authors, journals, institutions, and nations, covering a time span of
1991-1999.
The top 25 papers are ranked according to total cites. Rankings for author, journal, institution, and country are listed in three ways: according to total papers, total cites, and total cites/paper.
Ranking by total cites was used as the basis for determining which authors, journals, institutions, and countries to feature in our editorial section.
Schizophrenia
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