Label: Boule-2004
Title: Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
Journal: J EXP MED, 199 (12): 1631-1640 JUN 21 2004
Citations: 86
Authors: Boule, MW;Broughton, C;Mackay, F;Akira, S;Marshak-Rothstein, A;Rifkin, IR
Addresses:
Boston Univ, Sch Med, Dept Med, Renal Sect, EBRC 5th Floor,650 Albany St, Boston, MA 02118 USA
Boston Univ, Sch Med, Dept Med, Renal Sect, Boston, MA 02118 USA
Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02118 USA
Garvan Inst Med Res, Dept Arthrit & Inflammat, Darlinghurst, NSW 2010, Australia
Osaka Univ, Res Inst Microbial Dis, Suita, Osaka 5650871, Japan
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Label: Means-2005
Title: Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9
Journal: J CLIN INVEST, 115 (2): 407-417 FEB 2005
Citations: 80
Authors: Means, TK;Latz, E;Hayashi, F;Murali, MR;Golenbock, DT;Luster, AD
Addresses:
Massachusetts Gen Hosp, 149 13th St, Charlestown, MA 02129 USA
Massachusetts Gen Hosp, Charlestown, MA 02129 USA
Massachusetts Gen Hosp, Ctr Immunol & Inflammatory Dis, Boston, MA 02114 USA
Massachusetts Gen Hosp, Div Rheumatol Allergy & Immunol, Boston, MA 02114 USA
Harvard Univ, Sch Med, Boston, MA 02115 USA
Univ Massachusetts, Sch Med, Dept Med, Worcester, MA 01605 USA
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Label: Christensen-2005
Title: Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
Journal: J EXP MED, 202 (2): 321-331 JUL 18 2005
Citations: 60
Authors: Christensen, SR;Kashgarian, M;Alexopoulou, L;Flavell, RA;Akira, S;Shlomchik, MJ
Addresses:
Yale Univ, Sch Med, Immunobiol Sect, 333 Cedar St, New Haven, CT 06510 USA
Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06510 USA
Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06510 USA
Yale Univ, Sch Med, Dept Lab Med, New Haven, CT 06510 USA
Univ Mediterranee, CNRS, INSERM, Ctr Immunol Marseille Luminy, F-13288 Marseille, France
Osaka Univ, Res Inst Microbial Dis, Dept Host Def, Suita, Osaka 5650871, Japan
Japan Sci & Technol Corp, Exploratory Res Adv Technol, Akira Innate Immun Project, Suita, Osaka 5650871, Japan
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Label: Lau-2005
Title: RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
Journal: J EXP MED, 202 (9): 1171-1177 NOV 7 2005
Citations: 56
Authors: Lau, CM;Broughton, C;Tabor, AS;Akira, S;Flavell, RA;Mamula, MJ;Christensen, SR;Shlomchik, MJ;Viglianti, GA;Rifkin, IR;Marshak-Rothstein, A
Addresses:
Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02118 USA
Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02118 USA
Boston Univ, Sch Med, Dept Med, Boston, MA 02118 USA
Osaka Univ, Res Inst Microbial Dis, Suita, Osaka 5650871, Japan
Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06510 USA
Yale Univ, Sch Med, Rheumatol Sect, Dept Internal Med, New Haven, CT 06510 USA
Yale Univ, Sch Med, Dept Lab Med, New Haven, CT 06510 USA
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Label: Lovgren-2004
Title: Induction of interferon-a production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late anoptotic cells and lupus IgG
Journal: ARTHRITIS RHEUM, 50 (6): 1861-1872 JUN 2004
Citations: 55
Authors: Lovgren, T;Eloranta, ML;Bave, U;Alm, GV;Ronnblom, L
Addresses:
Biomed Ctr, POB 588, SE-75123 Uppsala, Sweden
Univ Uppsala, S-75105 Uppsala, Sweden
Swedish Univ Agr Sci, Uppsala, Sweden
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Label: Barrat-2005
Title: Nucleic acids of mammalian origin can act as endogenous ligands for toll-like receptors and may promote systemic lupus erythematosus
Journal: J EXP MED, 202 (8): 1131-1139 OCT 17 2005
Citations: 50
Authors: Barrat, FJ;Meeker, T;Gregorio, J;Chan, JH;Uematsu, S;Akira, S;Chang, B;Duramad, O;Coffman, RL
Addresses:
Dynavax Technol Corp, Berkeley, CA 94710 USA
Dynavax Technol Corp, Berkeley, CA 94710 USA
Osaka Univ, Res Inst Microbial Dis, Dept Host Def, Suita Ku, Suita, Osaka 5650871, Japan
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Label: Wandstrat-2004
Title: Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus
Journal: IMMUNITY, 21 (6): 769-780 DEC 2004
Citations: 44
Authors: Wandstrat, AE;Nguyen, C;Limaye, N;Chan, AY;Subramanian, S;Tian, XH;Yim, YS;Pertsemlidis, A;Garner, HR;Morel, L;Wakeland, EK
Addresses:
Univ Texas, SW Med Ctr, Ctr Immunol, 5323 Harry Hines Blvd, Dallas, TX 75235 USA
Univ Texas, SW Med Ctr, Ctr Immunol, Dallas, TX 75235 USA
Univ Texas, SW Med Ctr, Eugene McDermott Ctr Human Growth & Dev, Dallas, TX 75235 USA
Univ Florida, Sch Med, Dept Pathol & Lab Med, Gainesville, FL 32611 USA
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Label: Vollmer-2005
Title: Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8
Journal: J EXP MED, 202 (11): 1575-1585 DEC 5 2005
Citations: 37
Authors: Vollmer, J;Tluk, S;Schmitz, C;Hamm, S;Jurk, M;Forsbach, A;Akira, S;Kelly, KM;Reeves, WH;Bauer, S;Krieg, AM
Addresses:
Coley Pharmaceut Grp Inc, Wellesley, MA 02481 USA
Coley Pharmaceut Grp Inc, Wellesley, MA 02481 USA
Coley Pharmaceut GMBH, D-40764 Langenfeld, Germany
Inst Med Microbiol Hyg & Immunol, D-81675 Munich, Germany
Microbial Dis Res Inst, Dept Host Def, Suita, Osaka 5650871, Japan
Japan Sci & Technol Corp, ERATO, Osaka 5650047, Japan
Univ Florida, Gainesville, FL 32610 USA
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Label: Wu-2006
Title: Toll-like receptor 9 signaling protects against murine lupus
Journal: ARTHRITIS RHEUM, 54 (1): 336-342 JAN 2006
Citations: 22
Authors: Wu, XB;Peng, SL
Addresses:
Roche Palo Alto, Inflammat Autoimmun & Transplantat Res, 3431 Hillview Ave,Mailstop R7-101, Palo Alto, CA 94304 USA
Roche Palo Alto, Inflammat Autoimmun & Transplantat Res, Palo Alto, CA 94304 USA
Washington Univ, Sch Med, St Louis, MO USA
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Label: Pisitkun-2006
Title: Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
Journal: SCIENCE, 312 (5780): 1669-1672 JUN 16 2006
Citations: 18
Authors: Pisitkun, P;Deane, JA;Difilippantonio, MJ;Tarasenko, T;Satterthwaite, AB;Bolland, S
Addresses:
NIAID, Immunogenet Lab, NIH, Rockville, MD 20852 USA
NIAID, Immunogenet Lab, NIH, Rockville, MD 20852 USA
NCI, Sect Canc Genom, Henet Branch, Ctr Canc Res,NIH, Bethesda, MD 20892 USA
Univ Texas SW, Dept Internal Med, Dallas, TX 75390 USA
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Label: Ehlers-2006
Title: TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE
Journal: J EXP MED, 203 (3): 553-561 MAR 20 2006
Citations: 15
Authors: Ehlers, M;Fukuyama, H;McGaha, TL;Aderem, A;Ravetch, JV
Addresses:
Rockefeller Univ, Lab Mol Genet & Immunol, 1230 York Ave, New York, NY 10021 USA
Rockefeller Univ, Lab Mol Genet & Immunol, New York, NY 10021 USA
Inst Syst Biol, Seattle, WA 98103 USA
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Label: Savarese-2006
Title: U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7
Journal: BLOOD, 107 (8): 3229-3234 APR 15 2006
Citations: 14
Authors: Savarese, E;Chae, OW;Trowitzsch, S;Weber, G;Kastner, B;Akira, S;Wagner, H;Schmid, RM;Bauer, S;Krug, A
Addresses:
Tech Univ Munich, Klinikum Rechts Isar, Med Klin 2, Trogerstr 32,Raum 1-04, D-81675 Munich, Germany
Tech Univ Munich, Dept Internal Med, D-8000 Munich, Germany
Tech Univ Munich, Inst Microbiol & Immunol, D-8000 Munich, Germany
Max Planck Inst Biophys Chem, Dept Cellular Biochem, D-3400 Gottingen, Germany
Osaka Univ, Res Inst Microbial Dis, Dept Host Def, Osaka, Japan
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Label: Kumar-2006
Title: Regulation of B cell tolerance by the lupus susceptibility gene Ly108
Journal: SCIENCE, 312 (5780): 1665-1669 JUN 16 2006
Citations: 12
Authors: Kumar, KR;Li, LN;Yan, M;Bhaskarabhatla, M;Mobley, AB;Nguyen, C;Mooney, JM;Schatzle, JD;Wakeland, EK;Mohan, C
Addresses:
Univ Texas, SW Med Ctr, Dept Internal Med Rheumatol, Dallas, TX 75390 USA
Univ Texas, SW Med Ctr, Dept Internal Med Rheumatol, Dallas, TX 75390 USA
Univ Texas, SW Med Ctr, Ctr Immunol, Dallas, TX 75390 USA
Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75390 USA
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